A modified approach to 2-(N-aryl)-1,3-oxazoles: application to the synthesis of the IMPDH inhibitor BMS-337197 and analogues.

Dhar, T G Murali; Guo, Junqing; Shen, Zhongqi; Pitts, William J; Gu, Henry H; Chen, Bang-Chi; Zhao, Rulin; Bednarz, Mark S; Iwanowicz, Edwin J

Dhar, T G Murali; Guo, Junqing; Shen, Zhongqi; Pitts, William J; Gu, Henry H; Chen, Bang-Chi; Zhao, Rulin; Bednarz, Mark S; Iwanowicz, Edwin J.

Affiliation

Dhar TG; Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey 08543-4000, USA. dharm@bms.com

Org Lett ; 4(12): 2091-3, 2002 Jun 13.

Article in En | MEDLINE | ID: mdl-12049525

Subject(s)

Enzyme Inhibitors/chemical synthesis; IMP Dehydrogenase/antagonists & inhibitors; Oxazoles/chemical synthesis; Oxazoles/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Oxazoles / Enzyme Inhibitors / IMP Dehydrogenase Language: En Journal: Org Lett Journal subject: BIOQUIMICA Year: 2002 Type: Article Affiliation country: United States

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