Sheng-Mai-San is protective against post-ischemic myocardial dysfunction in rats through its opening of the mitochondrial KATP channels.

Wang, Ningyuan; Minatoguchi, Shinya; Arai, Masazumi; Uno, Yoshihiro; Nishida, Yoshio; Hashimoto, Kazuaki; Xue-Hai, Chen; Fukuda, Kazunori; Akao, Seigo; Takemura, Genzou; Fujiwara, Hisayoshi

Wang, Ningyuan; Minatoguchi, Shinya; Arai, Masazumi; Uno, Yoshihiro; Nishida, Yoshio; Hashimoto, Kazuaki; Xue-Hai, Chen; Fukuda, Kazunori; Akao, Seigo; Takemura, Genzou; Fujiwara, Hisayoshi.

Affiliation

Wang N; Second Department of Internal Medicine, Gifu University School of Medicine, Japan.

Circ J ; 66(8): 763-8, 2002 Aug.

Article in En | MEDLINE | ID: mdl-12197603

Subject(s)

Adenosine Triphosphate/metabolism; Cardiomyopathies/prevention & control; Cardiotonic Agents/therapeutic use; Drugs, Chinese Herbal/therapeutic use; Gentisates; Mitochondria, Heart/metabolism; Myocardial Ischemia/drug therapy; Potassium Channels/metabolism; Animals; Drug Combinations; Hydroxybenzoates/metabolism; In Vitro Techniques; L-Lactate Dehydrogenase/metabolism; Lactic Acid/metabolism; Male; Myocardial Ischemia/physiopathology; Myocardium/metabolism; Potassium Channels/drug effects; Rats; Rats, Sprague-Dawley; Recovery of Function; Ventricular Function, Left

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Collection: 01-internacional Database: MEDLINE Main subject: Drugs, Chinese Herbal / Cardiotonic Agents / Potassium Channels / Adenosine Triphosphate / Myocardial Ischemia / Gentisates / Mitochondria, Heart / Cardiomyopathies Limits: Animals Language: En Journal: Circ J Journal subject: ANGIOLOGIA / CARDIOLOGIA Year: 2002 Type: Article Affiliation country: Japan

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