In vivo correction of murine tyrosinemia type I by DNA-mediated transposition.

Montini, Eugenio; Held, Patrice K; Noll, Meenakshi; Morcinek, Nicolas; Al-Dhalimy, Muhsen; Finegold, Milton; Yant, Stephen R; Kay, Mark A; Grompe, Markus

Montini, Eugenio; Held, Patrice K; Noll, Meenakshi; Morcinek, Nicolas; Al-Dhalimy, Muhsen; Finegold, Milton; Yant, Stephen R; Kay, Mark A; Grompe, Markus.

Affiliation

Montini E; Department of Medical & Molecular Genetics, Oregon Health and Sciences University, Portland, Oregon 97239, USA.

Mol Ther ; 6(6): 759-69, 2002 Dec.

Article in En | MEDLINE | ID: mdl-12498772

Subject(s)

DNA Transposable Elements/genetics; Genetic Therapy/methods; Hydrolases/genetics; Hydrolases/metabolism; Recombination, Genetic/genetics; Tyrosinemias/genetics; Tyrosinemias/therapy; Animals; DNA/genetics; DNA/metabolism; Liver/enzymology; Liver/pathology; Mice; Mice, Knockout; Phenotype; Survival Rate; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Recombination, Genetic / DNA Transposable Elements / Genetic Therapy / Tyrosinemias / Hydrolases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2002 Type: Article Affiliation country: United States

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