Minimal tissue damage after stimulation of the motor thalamus in a case of chorea-acanthocytosis.

Burbaud, P; Vital, A; Rougier, A; Bouillot, S; Guehl, D; Cuny, E; Ferrer, X; Lagueny, A; Bioulac, B

Burbaud, P; Vital, A; Rougier, A; Bouillot, S; Guehl, D; Cuny, E; Ferrer, X; Lagueny, A; Bioulac, B.

Affiliation

Burbaud P; Department of Clinical Neurophysiology, Hôpital Pellegrin, Bordeaux, France. Pierre.Burbaud@umr5543.u-bordeaux2.fr

Neurology ; 59(12): 1982-4, 2002 Dec 24.

Article in En | MEDLINE | ID: mdl-12499498

ABSTRACT

ABSTRACT

Autopsy findings are reported from a patient with chorea-acanthocytosis treated for 2 years by deep brain stimulation (DBS) of the motor thalamus. Postoperative testing showed a progressive improvement in axial truncal spasms. Although relatively high currents were used for 2 years in this patient, postmortem analysis showed minimal tissue damage in the vicinity of the electrode tip. It is concluded that DBS has little impact on the surrounding tissues.

Subject(s)

Chorea/pathology; Chorea/therapy; Electric Stimulation Therapy/adverse effects; Thalamus/pathology; Thalamus/physiology; Adult; Autopsy; Chorea/complications; Electrodes, Implanted/adverse effects; Humans; Male; Radiography; Spasm/etiology; Spasm/therapy; Thalamus/diagnostic imaging

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Collection: 01-internacional Database: MEDLINE Main subject: Thalamus / Electric Stimulation Therapy / Chorea Type of study: Diagnostic_studies / Etiology_studies Limits: Adult / Humans / Male Language: En Journal: Neurology Year: 2002 Type: Article Affiliation country: France

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