Celecoxib versus diclofenac and omeprazole in reducing the risk of recurrent ulcer bleeding in patients with arthritis.

Chan, Francis K L; Hung, Lawrence C T; Suen, Bing Y; Wu, Justin C Y; Lee, Kenneth C; Leung, Vincent K S; Hui, Aric J; To, Ka F; Leung, Wai K; Wong, Vincent W S; Chung, S C Sydney; Sung, Joseph J Y

Chan, Francis K L; Hung, Lawrence C T; Suen, Bing Y; Wu, Justin C Y; Lee, Kenneth C; Leung, Vincent K S; Hui, Aric J; To, Ka F; Leung, Wai K; Wong, Vincent W S; Chung, S C Sydney; Sung, Joseph J Y.

Affiliation

Chan FK; Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, China. fklchan@cuhk.edu.hk

N Engl J Med ; 347(26): 2104-10, 2002 Dec 26.

Article in En | MEDLINE | ID: mdl-12501222

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/therapeutic use; Arthritis/drug therapy; Cyclooxygenase Inhibitors/therapeutic use; Peptic Ulcer Hemorrhage/prevention & control; Sulfonamides/therapeutic use; Anti-Inflammatory Agents, Non-Steroidal/adverse effects; Anti-Ulcer Agents/therapeutic use; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors/adverse effects; Diclofenac/adverse effects; Diclofenac/therapeutic use; Double-Blind Method; Drug Therapy, Combination; Duodenal Ulcer/chemically induced; Duodenal Ulcer/prevention & control; Helicobacter pylori/isolation & purification; Humans; Isoenzymes/antagonists & inhibitors; Membrane Proteins; Omeprazole/therapeutic use; Peptic Ulcer Hemorrhage/chemically induced; Probability; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Risk Factors; Secondary Prevention; Stomach Ulcer/chemically induced; Stomach Ulcer/prevention & control; Sulfonamides/adverse effects

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Collection: 01-internacional Database: MEDLINE Main subject: Arthritis / Sulfonamides / Peptic Ulcer Hemorrhage / Anti-Inflammatory Agents, Non-Steroidal / Cyclooxygenase Inhibitors Type of study: Clinical_trials / Etiology_studies / Guideline / Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: N Engl J Med Year: 2002 Type: Article Affiliation country: China

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