A prospective randomized pilot study to evaluate predictors of response in serial core biopsies to single agent neoadjuvant doxorubicin or paclitaxel for patients with locally advanced breast cancer.

Stearns, Vered; Singh, Baljit; Tsangaris, Theodore; Crawford, Jeanette G; Novielli, Antonella; Ellis, Mathew J; Isaacs, Claudine; Pennanen, Marie; Tibery, Cecilia; Farhad, Ahmad; Slack, Rebecca; Hayes, Daniel F

Stearns, Vered; Singh, Baljit; Tsangaris, Theodore; Crawford, Jeanette G; Novielli, Antonella; Ellis, Mathew J; Isaacs, Claudine; Pennanen, Marie; Tibery, Cecilia; Farhad, Ahmad; Slack, Rebecca; Hayes, Daniel F.

Affiliation

Stearns V; Department of Medicine, Lombardi Cancer Center, Georgetown University School of Medicine, Washington, DC 20007, USA. vstearn1@jhmi.edu

Clin Cancer Res ; 9(1): 124-33, 2003 Jan.

Article in En | MEDLINE | ID: mdl-12538460

Subject(s)

Breast Neoplasms/drug therapy; Doxorubicin/therapeutic use; Paclitaxel/therapeutic use; Adjuvants, Immunologic/pharmacology; Adult; Aged; Apoptosis; Biomarkers, Tumor; Biopsy; Breast Neoplasms/pathology; Cell Division; Clinical Trials as Topic; Female; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Middle Aged; Neoplasm Metastasis; Pilot Projects; Random Allocation; Time Factors; Treatment Outcome

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Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Doxorubicin / Paclitaxel Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2003 Type: Article Affiliation country: United States

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