PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect.

Tunaru, Sorin; Kero, Jukka; Schaub, Annette; Wufka, Christian; Blaukat, Andree; Pfeffer, Klaus; Offermanns, Stefan

Tunaru, Sorin; Kero, Jukka; Schaub, Annette; Wufka, Christian; Blaukat, Andree; Pfeffer, Klaus; Offermanns, Stefan.

Affiliation

Tunaru S; Institute of Pharmacology, University of Heidelberg, Heidelberg, Germany.

Nat Med ; 9(3): 352-5, 2003 Mar.

Article in En | MEDLINE | ID: mdl-12563315

Subject(s)

GTP-Binding Proteins/metabolism; Hypolipidemic Agents/metabolism; Niacin/metabolism; Receptors, Cell Surface/metabolism; Receptors, Nicotinic/metabolism; Adipose Tissue/metabolism; Animals; Cell Line; Cloning, Molecular; Fatty Acids, Nonesterified/metabolism; Genes, Reporter; Humans; Mice; Mice, Knockout; Molecular Sequence Data; Radioligand Assay; Receptors, Cell Surface/genetics; Receptors, G-Protein-Coupled; Receptors, Nicotinic/genetics; Tissue Distribution; Triglycerides/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Nicotinic / Receptors, Cell Surface / GTP-Binding Proteins / Hypolipidemic Agents / Niacin Limits: Animals / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2003 Type: Article Affiliation country: Germany

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