A randomized and blinded multicenter trial of high-dose fluconazole plus placebo versus fluconazole plus amphotericin B as therapy for candidemia and its consequences in nonneutropenic subjects.

Rex, John H; Pappas, Peter G; Karchmer, Adolf W; Sobel, Jack; Edwards, John E; Hadley, Susan; Brass, Corstiaan; Vazquez, Jose A; Chapman, Stanley W; Horowitz, Harold W; Zervos, Marcus; McKinsey, David; Lee, Jeannette; Babinchak, Timothy; Bradsher, Robert W; Cleary, John D; Cohen, David M; Danziger, Larry; Goldman, Mitchell; Goodman, Jesse; Hilton, Eileen; Hyslop, Newton E; Kett, Daniel H; Lutz, Jon; Rubin, Robert H; Scheld, W Michael; Schuster, Mindy; Simmons, Bryan; Stein, David K; Washburn, Ronald G; Mautner, Linda; Chu, Teng-Chiao; Panzer, Helene; Rosenstein, Rebecca B; Booth, Jenia

Rex, John H; Pappas, Peter G; Karchmer, Adolf W; Sobel, Jack; Edwards, John E; Hadley, Susan; Brass, Corstiaan; Vazquez, Jose A; Chapman, Stanley W; Horowitz, Harold W; Zervos, Marcus; McKinsey, David; Lee, Jeannette; Babinchak, Timothy; Bradsher, Robert W; Cleary, John D; Cohen, David M; Danziger, Larry; Goldman, Mitchell; Goodman, Jesse; Hilton, Eileen; Hyslop, Newton E; Kett, Daniel H; Lutz, Jon; Rubin, Robert H; Scheld, W Michael; Schuster, Mindy; Simmons, Bryan; Stein, David K; Washburn, Ronald G; Mautner, Linda; Chu, Teng-Chiao; Panzer, Helene; Rosenstein, Rebecca B; Booth, Jenia.

Affiliation

Rex JH; Division of Infectious Diseases, University of Texas Medical School, Houston, TX 77030, USA. john@rexweb.org

Clin Infect Dis ; 36(10): 1221-8, 2003 May 15.

Article in En | MEDLINE | ID: mdl-12746765

Subject(s)

Amphotericin B/therapeutic use; Antifungal Agents/therapeutic use; Candidiasis/drug therapy; Fluconazole/therapeutic use; Fungemia/drug therapy; Adult; Amphotericin B/adverse effects; Antifungal Agents/adverse effects; Candida/drug effects; Candidiasis/physiopathology; Catheterization; Double-Blind Method; Drug Therapy, Combination; Female; Fluconazole/adverse effects; Fungemia/physiopathology; Humans; Male; Middle Aged; Neutropenia/etiology; Treatment Outcome

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Candidiasis / Fluconazole / Amphotericin B / Fungemia / Antifungal Agents Type of study: Clinical_trials / Etiology_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Infect Dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2003 Type: Article Affiliation country: United States

Search on Google

XML

PubMed Links