BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect.

Hallahan, Andrew R; Pritchard, Joel I; Chandraratna, Roshantha A S; Ellenbogen, Richard G; Geyer, J Russel; Overland, Ryan P; Strand, Andrew D; Tapscott, Stephen J; Olson, James M

Hallahan, Andrew R; Pritchard, Joel I; Chandraratna, Roshantha A S; Ellenbogen, Richard G; Geyer, J Russel; Overland, Ryan P; Strand, Andrew D; Tapscott, Stephen J; Olson, James M.

Affiliation

Hallahan AR; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

Nat Med ; 9(8): 1033-8, 2003 Aug.

Article in En | MEDLINE | ID: mdl-12872164

Subject(s)

Apoptosis; Bone Morphogenetic Proteins/metabolism; Brain Neoplasms/metabolism; Medulloblastoma/metabolism; Paracrine Communication; Retinoids/pharmacology; Transforming Growth Factor beta; Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein Receptors; Brain Neoplasms/pathology; Female; Gene Expression Profiling; Humans; Medulloblastoma/pathology; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Oligonucleotide Array Sequence Analysis; Receptors, Growth Factor/genetics; Receptors, Growth Factor/metabolism; Transplantation, Heterologous; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Retinoids / Brain Neoplasms / Transforming Growth Factor beta / Apoptosis / Bone Morphogenetic Proteins / Paracrine Communication / Medulloblastoma Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2003 Type: Article Affiliation country: United States

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