Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin.

Bertilsson, L; Lou, Y Q; Du, Y L; Liu, Y; Kuang, T Y; Liao, X M; Wang, K Y; Reviriego, J; Iselius, L; Sjöqvist, F

Bertilsson, L; Lou, Y Q; Du, Y L; Liu, Y; Kuang, T Y; Liao, X M; Wang, K Y; Reviriego, J; Iselius, L; Sjöqvist, F.

Affiliation

Bertilsson L; Department of Clinical Pharmacology, Karolinska Institute, Huddinge Hospital, Sweden.

Clin Pharmacol Ther ; 51(4): 388-97, 1992 Apr.

Article in En | MEDLINE | ID: mdl-1345344

Subject(s)

Debrisoquin/metabolism; Mephenytoin/metabolism; China/ethnology; Chromatography, Gas; Debrisoquin/analogs & derivatives; Debrisoquin/urine; Humans; Hydroxylation; Phenotype; Polymorphism, Genetic; Sweden/ethnology

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Collection: 01-internacional Database: MEDLINE Main subject: Debrisoquin / Mephenytoin Limits: Humans Country/Region as subject: Asia / Europa Language: En Journal: Clin Pharmacol Ther Year: 1992 Type: Article Affiliation country: Sweden

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