Effects of escalating doses of recombinant human interleukin-2 in correcting functional T-cell defects following autologous bone marrow transplantation for lymphomas and solid tumors.

Bosly, A; Guillaume, T; Brice, P; Humblet, Y; Staquet, P; Doyen, C; Chatelain, B; Franks, C R; Gisselbrecht, C; Symann, M

Bosly, A; Guillaume, T; Brice, P; Humblet, Y; Staquet, P; Doyen, C; Chatelain, B; Franks, C R; Gisselbrecht, C; Symann, M.

Affiliation

Bosly A; Experimental Oncology and Hematology Laboratory, Catholic University of Louvain, Brussels, Belgium.

Exp Hematol ; 20(8): 962-8, 1992 Sep.

Article in En | MEDLINE | ID: mdl-1354620

Subject(s)

Bone Marrow Transplantation/pathology; Carcinoma, Small Cell/surgery; Choriocarcinoma/surgery; Interleukin-2/therapeutic use; Lung Neoplasms/surgery; Lymphoma/surgery; Ovarian Neoplasms/surgery; Recombinant Proteins/therapeutic use; T-Lymphocytes/immunology; Adult; Antigens, Differentiation, T-Lymphocyte/analysis; Blood Cell Count/drug effects; CD2 Antigens; CD8 Antigens/analysis; Cell Death/drug effects; Cell Division/drug effects; Dose-Response Relationship, Drug; Female; Humans; Immunologic Deficiency Syndromes/drug therapy; Infusions, Intravenous; Interleukin-2/administration & dosage; Interleukin-2/adverse effects; Killer Cells, Natural/drug effects; Killer Cells, Natural/physiology; Male; Middle Aged; Phenotype; Receptors, Immunologic/analysis; Receptors, Interleukin-2/analysis; Recombinant Proteins/administration & dosage; Recombinant Proteins/adverse effects; T-Lymphocytes/ultrastructure; Transplantation, Autologous

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Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Recombinant Proteins / T-Lymphocytes / Choriocarcinoma / Bone Marrow Transplantation / Interleukin-2 / Carcinoma, Small Cell / Lung Neoplasms / Lymphoma Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Exp Hematol Year: 1992 Type: Article Affiliation country: Belgium

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