Cytochrome P450 induction and mutagenicity of 2-aminoanthracene (2AA) in rat liver and gut.

Carrière, V; de Waziers, I; Courtois, Y A; Leroux, J P; Beaune, P H

Carrière, V; de Waziers, I; Courtois, Y A; Leroux, J P; Beaune, P H.

Affiliation

Carrière V; Inserm U75, Paris, France.

Mutat Res ; 268(1): 11-20, 1992 Jul.

Article in En | MEDLINE | ID: mdl-1378177

Subject(s)

Anthracenes/toxicity; Cytochrome P-450 Enzyme System/metabolism; Mutagens/toxicity; Acetone/pharmacology; Animals; Anthracenes/metabolism; Benzoflavones/pharmacology; Biotransformation; Blotting, Western; Colon/enzymology; Colon/metabolism; Dexamethasone/pharmacology; Intestine, Small/enzymology; Intestine, Small/metabolism; Liver/enzymology; Liver/metabolism; Male; Mutagenicity Tests; Mutagens/metabolism; Phenobarbital/pharmacology; Rats; Rats, Inbred Strains; Salmonella typhimurium/drug effects; beta-Naphthoflavone

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Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 Enzyme System / Anthracenes / Mutagens Limits: Animals Language: En Journal: Mutat Res Year: 1992 Type: Article Affiliation country: France

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