Selenoperoxidase-mediated cytoprotection against merocyanine 540-sensitized photoperoxidation and photokilling of leukemia cells.

Lin, F; Geiger, P G; Girotti, A W

Lin, F; Geiger, P G; Girotti, A W.

Affiliation

Lin F; Department of Biochemistry, Medical College of Wisconsin, Milwaukee 53226.

Cancer Res ; 52(19): 5282-90, 1992 Oct 01.

Article in En | MEDLINE | ID: mdl-1394132

Subject(s)

Glutathione Peroxidase/pharmacology; Leukemia L1210/enzymology; Leukemia, Experimental/enzymology; Lipid Peroxidation/drug effects; Photochemotherapy; Pyrimidinones/pharmacology; Radiation-Sensitizing Agents/pharmacology; Animals; Azoles/pharmacology; Catalase/pharmacology; Cell Death/drug effects; Cell Death/physiology; Cell Death/radiation effects; Glutathione/deficiency; Glutathione Peroxidase/antagonists & inhibitors; Humans; Isoindoles; Leukemia L1210/drug therapy; Leukemia L1210/metabolism; Leukemia, Experimental/drug therapy; Leukemia, Experimental/metabolism; Mice; Organoselenium Compounds/pharmacology; Phospholipid Hydroperoxide Glutathione Peroxidase; Pyrimidinones/toxicity; Radiation Tolerance/drug effects; Selenium/deficiency

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Collection: 01-internacional Database: MEDLINE Main subject: Photochemotherapy / Pyrimidinones / Radiation-Sensitizing Agents / Lipid Peroxidation / Leukemia, Experimental / Leukemia L1210 / Glutathione Peroxidase Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cancer Res Year: 1992 Type: Article

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