[Severely burned patients and atracurium: the train-of-four response]. / Grands brûlés et atracurium: réponse au train de quatre.
Cah Anesthesiol
; 40(5): 333-6, 1992.
Article
in Fr
| MEDLINE
| ID: mdl-1422930
ABSTRACT
Severely burned patients show a relative hyposensitivity to atracurium. The neuromuscular block obtained in 20 patients with major thermal injury after 0.75 mg.kg-1 i.v. of atracurium, by muscular activity recording (train of four-TOF), was studied. The results confirmed the resistance to atracurium, which mechanism is unknown. Even the doses administered, 50% higher than clinical dose (0.3-0.5 mg.kg-1), proved insufficient in order to obtain a complete neuromuscular block in severely burned patients.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Atracurium
/
Burns
/
Muscles
/
Neuromuscular Junction
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
Fr
Journal:
Cah Anesthesiol
Year:
1992
Type:
Article
Affiliation country:
Italy