Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes.

Kerlan, V; Dreano, Y; Bercovici, J P; Beaune, P H; Floch, H H; Berthou, F

Kerlan, V; Dreano, Y; Bercovici, J P; Beaune, P H; Floch, H H; Berthou, F.

Affiliation

Kerlan V; Laboratoire de Biochimie, Faculté de Médecine, Brest, France.

Biochem Pharmacol ; 44(9): 1745-56, 1992 Nov 03.

Article in En | MEDLINE | ID: mdl-1449532

Subject(s)

Cytochrome P-450 Enzyme System/metabolism; Estradiol/metabolism; Isoenzymes/metabolism; Microsomes, Liver/enzymology; Adolescent; Adult; Benzoflavones/pharmacology; Caffeine/pharmacology; Child, Preschool; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Female; Humans; Hydroxylation; Infant; Infant, Newborn; Isoenzymes/antagonists & inhibitors; Kinetics; Male; Middle Aged; Norpregnenes/pharmacology; Oxidoreductases/antagonists & inhibitors; Oxidoreductases/metabolism; Phenacetin/pharmacology; Progesterone Congeners/pharmacology; Tamoxifen/pharmacology; Testosterone/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Microsomes, Liver / Cytochrome P-450 Enzyme System / Estradiol / Isoenzymes Limits: Adolescent / Adult / Child, preschool / Female / Humans / Infant / Male / Middle aged / Newborn Language: En Journal: Biochem Pharmacol Year: 1992 Type: Article Affiliation country: France

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