A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

Bouwmeester, Tewis; Bauch, Angela; Ruffner, Heinz; Angrand, Pierre-Olivier; Bergamini, Giovanna; Croughton, Karen; Cruciat, Cristina; Eberhard, Dirk; Gagneur, Julien; Ghidelli, Sonja; Hopf, Carsten; Huhse, Bettina; Mangano, Raffaella; Michon, Anne-Marie; Schirle, Markus; Schlegl, Judith; Schwab, Markus; Stein, Martin A; Bauer, Andreas; Casari, Georg; Drewes, Gerard; Gavin, Anne-Claude; Jackson, David B; Joberty, Gerard; Neubauer, Gitte; Rick, Jens; Kuster, Bernhard; Superti-Furga, Giulio

Bouwmeester, Tewis; Bauch, Angela; Ruffner, Heinz; Angrand, Pierre-Olivier; Bergamini, Giovanna; Croughton, Karen; Cruciat, Cristina; Eberhard, Dirk; Gagneur, Julien; Ghidelli, Sonja; Hopf, Carsten; Huhse, Bettina; Mangano, Raffaella; Michon, Anne-Marie; Schirle, Markus; Schlegl, Judith; Schwab, Markus; Stein, Martin A; Bauer, Andreas; Casari, Georg; Drewes, Gerard; Gavin, Anne-Claude; Jackson, David B; Joberty, Gerard; Neubauer, Gitte; Rick, Jens; Kuster, Bernhard; Superti-Furga, Giulio.

Affiliation

Bouwmeester T; Cellzome AG, Meyerhofstrasse 1, 69117 Heidelberg, Germany. tewis.bouwmeester@cellzome.com

Nat Cell Biol ; 6(2): 97-105, 2004 Feb.

Article in En | MEDLINE | ID: mdl-14743216

Subject(s)

Drosophila Proteins; NF-kappa B/metabolism; Signal Transduction/physiology; Tumor Necrosis Factor-alpha/metabolism; Animals; Carrier Proteins/genetics; Carrier Proteins/metabolism; Cell Cycle Proteins/genetics; Cell Cycle Proteins/metabolism; Cell Line; Chaperonins; Chromatography, Affinity/methods; Enzyme Activation; HSP90 Heat-Shock Proteins/genetics; HSP90 Heat-Shock Proteins/metabolism; Humans; I-kappa B Proteins/isolation & purification; I-kappa B Proteins/metabolism; MAP Kinase Kinase Kinase 3; MAP Kinase Kinase Kinases/genetics; MAP Kinase Kinase Kinases/metabolism; Macromolecular Substances; Mass Spectrometry/methods; Models, Biological; Molecular Chaperones/genetics; Molecular Chaperones/metabolism; NF-kappa B/genetics; NF-kappa B/isolation & purification; Proteome/analysis; RNA Interference; Receptors, Tumor Necrosis Factor/metabolism; Tacrolimus Binding Proteins/genetics; Tacrolimus Binding Proteins/metabolism; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/isolation & purification; Tumor Suppressor Proteins/genetics; Tumor Suppressor Proteins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / NF-kappa B / Tumor Necrosis Factor-alpha / Drosophila Proteins Type of study: Prognostic_studies Language: En Journal: Nat Cell Biol Year: 2004 Type: Article Affiliation country: Germany

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