A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex.

Raghavan, Sathees C; Swanson, Patrick C; Wu, Xiantuo; Hsieh, Chih-Lin; Lieber, Michael R

Raghavan, Sathees C; Swanson, Patrick C; Wu, Xiantuo; Hsieh, Chih-Lin; Lieber, Michael R.

Affiliation

Raghavan SC; Norris Comprehensive Cancer Center, Room 5428, University of Southern California Keck School of Medicine, 1441 Eastlake Ave., MC9176, Los Angeles, California 90033, USA.

Nature ; 428(6978): 88-93, 2004 Mar 04.

Article in En | MEDLINE | ID: mdl-14999286

Subject(s)

Chromosome Breakage/genetics; DNA-Binding Proteins/metabolism; DNA/chemistry; DNA/genetics; Genes, bcl-2/genetics; Homeodomain Proteins/metabolism; Nucleic Acid Conformation; Animals; Cell Line; Chromosomes, Human, Pair 14/genetics; Chromosomes, Human, Pair 18/genetics; DNA-Binding Proteins/genetics; Homeodomain Proteins/genetics; Humans; Macromolecular Substances; Mice; Nuclear Proteins; Plasmids/genetics; Proto-Oncogene Proteins c-bcl-2/genetics; Recombination, Genetic/genetics; Sulfites/metabolism; Translocation, Genetic/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: DNA / Homeodomain Proteins / Chromosome Breakage / Genes, bcl-2 / DNA-Binding Proteins / Nucleic Acid Conformation Limits: Animals / Humans Language: En Journal: Nature Year: 2004 Type: Article Affiliation country: United States

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