Combined administration of taurine and meso 2,3-dimercaptosuccinic acid in the treatment of chronic lead intoxication in rats.

Flora, S J S; Pande, Manisha; Bhadauria, Smrati; Kannan, G M

Flora, S J S; Pande, Manisha; Bhadauria, Smrati; Kannan, G M.

Affiliation

Flora SJ; Division of Pharmacology and Toxicology, Defence Research and Development Establishment, Jhansi Road, Gwalior 474 002, India. sjsflora@hotmail.com

Hum Exp Toxicol ; 23(4): 157-66, 2004 Apr.

Article in En | MEDLINE | ID: mdl-15171566

Subject(s)

Antioxidants/therapeutic use; Chelating Agents/therapeutic use; Lead Poisoning/drug therapy; Succimer/therapeutic use; Taurine/therapeutic use; Aminolevulinic Acid/blood; Animals; Antioxidants/administration & dosage; Brain/enzymology; Brain/metabolism; Chelating Agents/administration & dosage; Drug Therapy, Combination; Erythrocytes/metabolism; Glutathione/metabolism; Kidney/metabolism; Lead Poisoning/metabolism; Liver/enzymology; Liver/metabolism; Male; Organometallic Compounds/poisoning; Oxidative Stress/drug effects; Protoporphyrins/metabolism; Rats; Rats, Wistar; Succimer/administration & dosage; Superoxide Dismutase/metabolism; Taurine/administration & dosage; Thiobarbituric Acid Reactive Substances/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Taurine / Chelating Agents / Succimer / Lead Poisoning / Antioxidants Limits: Animals Language: En Journal: Hum Exp Toxicol Journal subject: TOXICOLOGIA Year: 2004 Type: Article Affiliation country: India

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