Synthesis and biological relationships of 3',6-substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives as antimitotic agents.

Lai, Ya-Yun; Huang, Li-Jiau; Lee, Kuo-Hsiung; Xiao, Zhiyan; Bastow, Kenneth F; Yamori, Takao; Kuo, Sheng-Chu

Lai, Ya-Yun; Huang, Li-Jiau; Lee, Kuo-Hsiung; Xiao, Zhiyan; Bastow, Kenneth F; Yamori, Takao; Kuo, Sheng-Chu.

Affiliation

Lai YY; Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung, Taiwan.

Bioorg Med Chem ; 13(1): 265-75, 2005 Jan 03.

Article in En | MEDLINE | ID: mdl-15582470

Subject(s)

Antineoplastic Agents/chemical synthesis; Antineoplastic Agents/pharmacology; Mitosis/drug effects; Quinolones/chemical synthesis; Quinolones/pharmacology; Antineoplastic Agents/chemistry; Carboxylic Acids/chemistry; Cell Line, Tumor; Humans; Magnetic Resonance Spectroscopy; Quinolones/chemistry; Spectrophotometry, Infrared

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Collection: 01-internacional Database: MEDLINE Main subject: Quinolones / Mitosis / Antineoplastic Agents Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2005 Type: Article Affiliation country: Taiwan

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