Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin-2 and interferon in patients with metastatic renal cell carcinoma.

McDermott, David F; Regan, Meredith M; Clark, Joseph I; Flaherty, Lawrence E; Weiss, Geoffery R; Logan, Theodore F; Kirkwood, John M; Gordon, Michael S; Sosman, Jeffrey A; Ernstoff, Marc S; Tretter, Christopher P G; Urba, Walter J; Smith, John W; Margolin, Kim A; Mier, James W; Gollob, Jared A; Dutcher, Janice P; Atkins, Michael B

McDermott, David F; Regan, Meredith M; Clark, Joseph I; Flaherty, Lawrence E; Weiss, Geoffery R; Logan, Theodore F; Kirkwood, John M; Gordon, Michael S; Sosman, Jeffrey A; Ernstoff, Marc S; Tretter, Christopher P G; Urba, Walter J; Smith, John W; Margolin, Kim A; Mier, James W; Gollob, Jared A; Dutcher, Janice P; Atkins, Michael B.

Affiliation

McDermott DF; Department of Medicine, Division of Hematology/Oncology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, E/KS-153, Boston, MA 02215, USA. dmcdermo@bidmc.harvard.edu

J Clin Oncol ; 23(1): 133-41, 2005 Jan 01.

Article in En | MEDLINE | ID: mdl-15625368

Subject(s)

Antineoplastic Agents/administration & dosage; Carcinoma, Renal Cell/drug therapy; Interferon-alpha/administration & dosage; Interleukin-2/administration & dosage; Kidney Neoplasms/drug therapy; Adult; Aged; Carcinoma, Renal Cell/mortality; Female; Humans; Injections, Subcutaneous; Interferon alpha-2; Kidney Neoplasms/mortality; Male; Middle Aged; Neoplasm Metastasis; Recombinant Proteins; Survival Rate

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Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Renal Cell / Interleukin-2 / Interferon-alpha / Kidney Neoplasms / Antineoplastic Agents Type of study: Clinical_trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Clin Oncol Year: 2005 Type: Article Affiliation country: United States

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