The role of impaired insulin/IGF action in primary diabetic encephalopathy.

Li, Zhen-Guo; Zhang, Weixian; Sima, Anders A F

Li, Zhen-Guo; Zhang, Weixian; Sima, Anders A F.

Affiliation

Li ZG; Department of Pathology, Wayne State University, School of Medicine, H.G. Scott Hall, Room 9275, 540 East Canfield Avenue, Detroit, MI 48201, USA.

Brain Res ; 1037(1-2): 12-24, 2005 Mar 10.

Article in En | MEDLINE | ID: mdl-15777748

Subject(s)

Diabetes Mellitus, Type 1/physiopathology; Diabetes Mellitus, Type 2/physiopathology; Diabetic Nephropathies/physiopathology; Insulin/physiology; Somatomedins/physiology; Animals; Apoptosis; Blotting, Western; Caspases/physiology; DNA Fragmentation; Diabetes Mellitus, Type 1/genetics; Diabetes Mellitus, Type 2/genetics; Diabetic Nephropathies/pathology; Hippocampus/pathology; Hyperglycemia/pathology; Hyperglycemia/physiopathology; Immunohistochemistry; In Situ Nick-End Labeling; Insulin/blood; Male; Neurons/pathology; Oxidative Stress/physiology; Poly(ADP-ribose) Polymerases/metabolism; Rats; Rats, Inbred BB; Rats, Wistar; Receptor Protein-Tyrosine Kinases/metabolism; Receptors, Tumor Necrosis Factor/metabolism; Reverse Transcriptase Polymerase Chain Reaction; fas Receptor/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Somatomedins / Diabetes Mellitus, Type 1 / Diabetes Mellitus, Type 2 / Diabetic Nephropathies / Insulin Limits: Animals Language: En Journal: Brain Res Year: 2005 Type: Article Affiliation country: United States

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