HSP25 inhibits radiation-induced apoptosis through reduction of PKCdelta-mediated ROS production.

Lee, Yoon-Jin; Lee, Dae-Hoon; Cho, Chul-Koo; Chung, Hee-Yong; Bae, Sangwoo; Jhon, Gil-Ja; Soh, Jae-Won; Jeoung, Doo-Il; Lee, Su-Jae; Lee, Yun-Sil

Lee, Yoon-Jin; Lee, Dae-Hoon; Cho, Chul-Koo; Chung, Hee-Yong; Bae, Sangwoo; Jhon, Gil-Ja; Soh, Jae-Won; Jeoung, Doo-Il; Lee, Su-Jae; Lee, Yun-Sil.

Affiliation

Lee YJ; Laboratory of Radiation Effect, Division of Radiation Biology, Korea Institute of Radiological and Medical Sciences, 215-4 Gongneung-Dong, Nowon-Ku, Seoul 139-706, Korea.

Oncogene ; 24(23): 3715-25, 2005 May 26.

Article in En | MEDLINE | ID: mdl-15806174

Subject(s)

Apoptosis/radiation effects; Heat-Shock Proteins/physiology; Neoplasm Proteins/physiology; Protein Kinase C/physiology; Reactive Oxygen Species/metabolism; Enzyme Activation; HSP27 Heat-Shock Proteins; Humans; Jurkat Cells; Mitochondria/physiology; Molecular Chaperones; Phosphorylation; Protein Kinase C-delta; p38 Mitogen-Activated Protein Kinases/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase C / Reactive Oxygen Species / Apoptosis / Heat-Shock Proteins / Neoplasm Proteins Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2005 Type: Article

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