Tachyplesin activates the classic complement pathway to kill tumor cells.

Chen, Jinguo; Xu, Xue-Ming; Underhill, Charles B; Yang, Shanmin; Wang, Luping; Chen, Yixin; Hong, Shuigen; Creswell, Karen; Zhang, Lurong

Chen, Jinguo; Xu, Xue-Ming; Underhill, Charles B; Yang, Shanmin; Wang, Luping; Chen, Yixin; Hong, Shuigen; Creswell, Karen; Zhang, Lurong.

Affiliation

Chen J; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia, USA.

Cancer Res ; 65(11): 4614-22, 2005 Jun 01.

Article in En | MEDLINE | ID: mdl-15930279

Subject(s)

Antimicrobial Cationic Peptides/pharmacology; Complement Pathway, Classical/drug effects; DNA-Binding Proteins/pharmacology; Peptides, Cyclic/pharmacology; Amino Acid Sequence; Antimicrobial Cationic Peptides/immunology; Antimicrobial Cationic Peptides/metabolism; Cell Line, Tumor; Complement C1q/metabolism; Complement C3b/immunology; Complement C3b/metabolism; Complement C4b/immunology; Complement C4b/metabolism; DNA-Binding Proteins/immunology; DNA-Binding Proteins/metabolism; Flow Cytometry; Humans; Hyaluronic Acid/immunology; Hyaluronic Acid/metabolism; Molecular Sequence Data; Peptide Library; Peptides, Cyclic/immunology; Peptides, Cyclic/metabolism; Urinary Bladder Neoplasms/drug therapy; Urinary Bladder Neoplasms/immunology; Urinary Bladder Neoplasms/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Peptides, Cyclic / Complement Pathway, Classical / Antimicrobial Cationic Peptides / DNA-Binding Proteins Limits: Humans Language: En Journal: Cancer Res Year: 2005 Type: Article Affiliation country: United States

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