Probucol enhances the expression of human hepatic scavenger receptor class B type I, possibly through a species-specific mechanism.

Hirano, Ken-ichi; Ikegami, Chiaki; Tsujii, Ken-ichi; Zhang, Zhongyan; Matsuura, Fumihiko; Nakagawa-Toyama, Yumiko; Koseki, Masahiro; Masuda, Daisaku; Maruyama, Takao; Shimomura, Iichiro; Ueda, Yukihiko; Yamashita, Shizuya

Hirano, Ken-ichi; Ikegami, Chiaki; Tsujii, Ken-ichi; Zhang, Zhongyan; Matsuura, Fumihiko; Nakagawa-Toyama, Yumiko; Koseki, Masahiro; Masuda, Daisaku; Maruyama, Takao; Shimomura, Iichiro; Ueda, Yukihiko; Yamashita, Shizuya.

Affiliation

Hirano K; Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan. khirano@kb3.so-net.ne.jp

Arterioscler Thromb Vasc Biol ; 25(11): 2422-7, 2005 Nov.

Article in En | MEDLINE | ID: mdl-16151015

Subject(s)

Anticholesteremic Agents/pharmacology; Atherosclerosis/drug therapy; Hepatocytes/drug effects; Probucol/pharmacology; Scavenger Receptors, Class B/genetics; Adult; Animals; Atherosclerosis/physiopathology; Carcinoma, Hepatocellular; Cell Line, Tumor; Cycloheximide/pharmacology; Disease Models, Animal; Gene Expression/drug effects; Hepatocytes/cytology; Hepatocytes/physiology; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Protein Synthesis Inhibitors/pharmacology; RNA, Messenger/analysis; Rabbits; Species Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Probucol / Hepatocytes / Atherosclerosis / Scavenger Receptors, Class B / Anticholesteremic Agents Limits: Adult / Animals / Humans / Male Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2005 Type: Article Affiliation country: Japan

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