[Immunologic phenotype of lymphocytes in chronic B-cell lymphocytic leukemia. II. Studies of immunologic phenotype of peripheral blood and lymph node lymphocytes in patients with chronic lymphocytic leukemia or leukemic forms of lymphoplasmacytoid lymphoma]. / Fenotyp immunologiczny limfocytów przewleklej bialaczki limfatycznej B-komórkowej. Czesc II. Badania wlasne fenotypu immunologicznego limfocytów krwi obwodowej i wezla chlonnego u chorych na przewlekla bialaczke limfatyczna, lub bialaczkowa postac chloniaka limfoplazmocytoidalnego.

ABSTRACT

UNLABELLED In a group of 16 patients with chronic lymphocytic leukaemia and leukaemic forms of the lymphoma lymphoplasmocytoides immunophenotypes of peripheral blood and lymph node lymphocytes were studied. CONCLUSIONS: 1) immunophenotype heterogeneity observed in a minority of patients in lymph-nodes or peripheral blood seems to be connected with the co-existence of leukaemic and normal reactive B-cells, 2) SIgG+ cells seem to represent activated B lymphocytes producing and secreting autoantibodies, 3) circulating peripheral T lymphocytes do not reflect the distribution of T cell subpopulations in lymph-nodes.