The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein.

Kumar, S; Rabson, A B; Gélinas, C

Kumar, S; Rabson, A B; Gélinas, C.

Affiliation

Kumar S; Center for Advanced Biotechnology and Medicine, Piscataway, New Jersey 08854-5638.

Mol Cell Biol ; 12(7): 3094-106, 1992 Jul.

Article in En | MEDLINE | ID: mdl-1620118

Subject(s)

DNA-Binding Proteins/genetics; Oncogenes/genetics; Retroviridae Proteins, Oncogenic/genetics; Base Sequence; Binding Sites; Consensus Sequence; Cysteine; DNA Mutational Analysis; Humans; Molecular Sequence Data; Multigene Family; Mutagenesis, Site-Directed; Oncogene Proteins v-rel; Oxidation-Reduction; Serine; Transcription, Genetic; Transformation, Genetic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oncogenes / Retroviridae Proteins, Oncogenic / DNA-Binding Proteins Limits: Humans Language: En Journal: Mol Cell Biol Year: 1992 Type: Article

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