Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad7.

Inamoto, S; Iwata, S; Inamoto, T; Nomura, S; Sasaki, T; Urasaki, Y; Hosono, O; Kawasaki, H; Tanaka, H; Dang, N H; Morimoto, C

Inamoto, S; Iwata, S; Inamoto, T; Nomura, S; Sasaki, T; Urasaki, Y; Hosono, O; Kawasaki, H; Tanaka, H; Dang, N H; Morimoto, C.

Affiliation

Inamoto S; Division of Clinical Immunology, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

Oncogene ; 26(6): 893-904, 2007 Feb 08.

Article in En | MEDLINE | ID: mdl-16909115

Subject(s)

Adaptor Proteins, Signal Transducing/metabolism; Phosphoproteins/metabolism; Signal Transduction; Smad6 Protein/antagonists & inhibitors; Smad7 Protein/antagonists & inhibitors; Transforming Growth Factor beta/metabolism; Activin Receptors, Type I/metabolism; Adaptor Proteins, Signal Transducing/genetics; Cell Line; Cell Proliferation; Humans; Phosphoproteins/genetics; Protein Binding; Protein Serine-Threonine Kinases; RNA, Small Interfering/genetics; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta/metabolism; Smad Proteins, Inhibitory/metabolism; Smad6 Protein/genetics; Smad6 Protein/metabolism; Smad7 Protein/genetics; Smad7 Protein/metabolism; Transcription, Genetic/genetics; Transforming Growth Factor beta/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Signal Transduction / Transforming Growth Factor beta / Adaptor Proteins, Signal Transducing / Smad6 Protein / Smad7 Protein Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2007 Type: Article Affiliation country: Japan

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