Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer.

Chan, Tsun Leung; Yuen, Siu Tsan; Kong, Chi Kwan; Chan, Yee Wai; Chan, Annie S Y; Ng, Wai Fu; Tsui, Wai Yin; Lo, Michelle W S; Tam, Wing Yip; Li, Vivian S W; Leung, Suet Yi

Chan, Tsun Leung; Yuen, Siu Tsan; Kong, Chi Kwan; Chan, Yee Wai; Chan, Annie S Y; Ng, Wai Fu; Tsui, Wai Yin; Lo, Michelle W S; Tam, Wing Yip; Li, Vivian S W; Leung, Suet Yi.

Affiliation

Chan TL; Hereditary Gastrointestinal Cancer Genetic Diagnosis Laboratory, Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.

Nat Genet ; 38(10): 1178-83, 2006 Oct.

Article in En | MEDLINE | ID: mdl-16951683

Subject(s)

Colorectal Neoplasms, Hereditary Nonpolyposis/genetics; MutS Homolog 2 Protein/genetics; Adult; Colorectal Neoplasms, Hereditary Nonpolyposis/pathology; DNA Methylation; Female; Germ-Line Mutation; Humans; Male; Pedigree

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Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms, Hereditary Nonpolyposis / MutS Homolog 2 Protein Limits: Adult / Female / Humans / Male Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2006 Type: Article Affiliation country: Hong Kong

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