E2F3 is the main target gene of the 6p22 amplicon with high specificity for human bladder cancer.

Oeggerli, M; Schraml, P; Ruiz, C; Bloch, M; Novotny, H; Mirlacher, M; Sauter, G; Simon, R

Oeggerli, M; Schraml, P; Ruiz, C; Bloch, M; Novotny, H; Mirlacher, M; Sauter, G; Simon, R.

Affiliation

Oeggerli M; Department of Molecular Pathology, Institute of Pathology, University of Basel, Basel, Switzerland. martin.oeggerli@unibas.ch

Oncogene ; 25(49): 6538-43, 2006 Oct 19.

Article in En | MEDLINE | ID: mdl-16953223

Subject(s)

Chromosomes, Human, Pair 6; E2F3 Transcription Factor/genetics; Gene Amplification; Urinary Bladder Neoplasms/genetics; Cell Proliferation/drug effects; Chromosomes, Artificial, Bacterial; Chromosomes, Artificial, P1 Bacteriophage; Gene Dosage; Gene Expression Regulation, Neoplastic; Humans; Prognosis; RNA, Small Interfering/pharmacology; Tissue Array Analysis/methods

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Collection: 01-internacional Database: MEDLINE Main subject: Urinary Bladder Neoplasms / Chromosomes, Human, Pair 6 / Gene Amplification / E2F3 Transcription Factor Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2006 Type: Article Affiliation country: Switzerland

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