Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin.

Ma, Peisong; Beck, Shannon L; Raab, Ronald W; McKown, Robert L; Coffman, George L; Utani, Atsushi; Chirico, William J; Rapraeger, Alan C; Laurie, Gordon W

Ma, Peisong; Beck, Shannon L; Raab, Ronald W; McKown, Robert L; Coffman, George L; Utani, Atsushi; Chirico, William J; Rapraeger, Alan C; Laurie, Gordon W.

Affiliation

Ma P; Department of Cell Biology, University of Virginia, Charlottesville, VA 22908, USA.

J Cell Biol ; 174(7): 1097-106, 2006 Sep 25.

Article in En | MEDLINE | ID: mdl-16982797

Subject(s)

Epithelial Cells/metabolism; Glucuronidase/pharmacology; Glycoproteins/metabolism; Growth Substances/metabolism; Membrane Glycoproteins/metabolism; Polysaccharides/metabolism; Proteoglycans/metabolism; Cell Line; Fibroblast Growth Factor 2/metabolism; Humans; Membrane Glycoproteins/drug effects; Membrane Proteins/metabolism; Models, Biological; Protein Binding; Protein Structure, Tertiary; Proteoglycans/drug effects; Syndecan-1; Syndecans

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides / Proteoglycans / Membrane Glycoproteins / Glycoproteins / Growth Substances / Epithelial Cells / Glucuronidase Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Cell Biol Year: 2006 Type: Article Affiliation country: United States

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