Therapeutic efficacy of intra-cochlear administration of methylprednisolone after acoustic trauma caused by gunshot noise in guinea pigs.

Sendowski, I; Abaamrane, L; Raffin, F; Cros, A; Clarençon, D

Sendowski, I; Abaamrane, L; Raffin, F; Cros, A; Clarençon, D.

Affiliation

Sendowski I; Centre de recherches du service de santé des armées (CRSSA), Département de radiobiologie, 24 avenue des Maquis du Grésivaudan, BP 87, 38702 La Tronche Cedex, France. isendowski@crssa.net

Hear Res ; 221(1-2): 119-27, 2006 Nov.

Article in En | MEDLINE | ID: mdl-17008037

Subject(s)

Cochlea/drug effects; Hearing Loss, Noise-Induced/drug therapy; Methylprednisolone/administration & dosage; Action Potentials/drug effects; Animals; Firearms; Guinea Pigs; Hair Cells, Auditory, Inner/drug effects; Hair Cells, Auditory, Inner/pathology; Hair Cells, Auditory, Outer/drug effects; Hair Cells, Auditory, Outer/pathology; Hearing Loss, Noise-Induced/etiology; Hearing Loss, Noise-Induced/pathology; Hearing Loss, Noise-Induced/physiopathology; NF-kappa B/physiology; Nitric Oxide/physiology; Oxidative Stress/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Methylprednisolone / Cochlea / Hearing Loss, Noise-Induced Type of study: Etiology_studies Limits: Animals Language: En Journal: Hear Res Year: 2006 Type: Article Affiliation country: France

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