Pharmacokinetics of 125I-GST-TatdMt, a recombinant fusion protein possessing potent anti-obesity activity, after intravenous, nasal, oral, and subcutaneous administration.

Shin, Beom Soo; Kim, Chul Hwan; Lee, Min-Nyung; Hur, Man-Wook; Lee, Kang Choon; Youn, Yu Seok; Yoo, Sun Dong

Shin, Beom Soo; Kim, Chul Hwan; Lee, Min-Nyung; Hur, Man-Wook; Lee, Kang Choon; Youn, Yu Seok; Yoo, Sun Dong.

Affiliation

Shin BS; College of Pharmacy, Sungkyunkwan University, 300 Cheoncheon-dong, Jangan-gu, Suwon, Kyeonggi-do, 440-746, Republic of Korea.

Regul Pept ; 140(1-2): 74-80, 2007 Apr 05.

Article in En | MEDLINE | ID: mdl-17175039

Subject(s)

Gene Products, tat/pharmacokinetics; Glutathione Transferase/pharmacokinetics; Obesity/drug therapy; Recombinant Fusion Proteins/pharmacokinetics; Administration, Intranasal; Administration, Oral; Animals; Gene Products, tat/administration & dosage; Gene Products, tat/genetics; Glutathione Transferase/administration & dosage; Glutathione Transferase/genetics; Injections, Intravenous; Injections, Subcutaneous; Iodine Radioisotopes; Male; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins/administration & dosage; Recombinant Fusion Proteins/genetics; Time Factors; Tissue Distribution

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Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Fusion Proteins / Gene Products, tat / Glutathione Transferase / Obesity Limits: Animals Language: En Journal: Regul Pept Year: 2007 Type: Article

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