Cellular penetration and nuclear importation properties of 111In-labeled and 123I-labeled HIV-1 tat peptide immunoconjugates in BT-474 human breast cancer cells.

Cornelissen, Bart; Hu, Meiduo; McLarty, Kristin; Costantini, Dan; Reilly, Raymond M

Cornelissen, Bart; Hu, Meiduo; McLarty, Kristin; Costantini, Dan; Reilly, Raymond M.

Affiliation

Cornelissen B; Division of Nuclear Medicine, University Health Network, Toronto, ON, Canada M5S 3M2.

Nucl Med Biol ; 34(1): 37-46, 2007 Jan.

Article in En | MEDLINE | ID: mdl-17210460

Subject(s)

Breast Neoplasms/metabolism; Cell Nucleus/metabolism; Drug Delivery Systems/methods; Gene Products, tat/pharmacokinetics; Immunoconjugates/pharmacokinetics; Indium Radioisotopes/pharmacokinetics; Iodine Radioisotopes/pharmacokinetics; Breast Neoplasms/diagnostic imaging; Cell Line, Tumor; Cell Nucleus/diagnostic imaging; Gene Products, tat/chemistry; Humans; Immunoconjugates/chemistry; Indium Radioisotopes/chemistry; Iodine Radioisotopes/chemistry; Metabolic Clearance Rate; Radionuclide Imaging; Radiopharmaceuticals/chemistry; Radiopharmaceuticals/pharmacokinetics

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Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Indium Radioisotopes / Gene Products, tat / Cell Nucleus / Drug Delivery Systems / Immunoconjugates / Iodine Radioisotopes Limits: Humans Language: En Journal: Nucl Med Biol Journal subject: BIOLOGIA / MEDICINA NUCLEAR Year: 2007 Type: Article

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