Bmp2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoter.

Chandler, Ronald L; Chandler, Kelly J; McFarland, Karen A; Mortlock, Douglas P

Chandler, Ronald L; Chandler, Kelly J; McFarland, Karen A; Mortlock, Douglas P.

Affiliation

Chandler RL; Department of Molecular Physiology and Biophysics, Center for Human Genetics Research, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

Mol Cell Biol ; 27(8): 2934-51, 2007 Apr.

Article in En | MEDLINE | ID: mdl-17283059

Subject(s)

Base Pairing/genetics; Bone Morphogenetic Proteins/genetics; Enhancer Elements, Genetic/genetics; Osteoblasts/metabolism; Promoter Regions, Genetic/genetics; Stem Cells/metabolism; Transcription, Genetic; Transforming Growth Factor beta/genetics; 3' Flanking Region/genetics; Animals; Biomarkers; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins/metabolism; Bone and Bones/embryology; Bone and Bones/metabolism; Cell Differentiation; Embryo, Mammalian/metabolism; Gene Expression Profiling; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Osteoblasts/cytology; RNA, Messenger/genetics; RNA, Messenger/metabolism; Sequence Deletion; Stem Cells/cytology; Tooth/cytology; Transforming Growth Factor beta/metabolism; Transgenes; beta-Galactosidase/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoblasts / Stem Cells / Transcription, Genetic / Transforming Growth Factor beta / Enhancer Elements, Genetic / Promoter Regions, Genetic / Bone Morphogenetic Proteins / Base Pairing Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Mol Cell Biol Year: 2007 Type: Article Affiliation country: United States

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