CD40.FasL inhibits human T cells: evidence for an auto-inhibitory loop-back mechanism.

Dranitzki-Elhalel, M; Huang, J H; Sasson, M; Rachmilewitz, J; Parnas, M; Tykocinski, M L

Dranitzki-Elhalel, M; Huang, J H; Sasson, M; Rachmilewitz, J; Parnas, M; Tykocinski, M L.

Affiliation

Dranitzki-Elhalel M; Nephrology and Hypertension Services, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. michalelhalel@gmail.com

Int Immunol ; 19(4): 355-63, 2007 Apr.

Article in En | MEDLINE | ID: mdl-17314083

Subject(s)

Apoptosis/drug effects; CD40 Antigens/genetics; Fas Ligand Protein/genetics; Recombinant Fusion Proteins/pharmacology; T-Lymphocytes/drug effects; Animals; Antibodies, Monoclonal/immunology; Antibodies, Monoclonal/pharmacology; B-Lymphocytes/cytology; B-Lymphocytes/drug effects; B-Lymphocytes/metabolism; CD3 Complex/immunology; CD40 Antigens/metabolism; CD40 Ligand/genetics; CD40 Ligand/metabolism; CD8 Antigens/genetics; CD8 Antigens/metabolism; Cell Line; Cell Line, Tumor; Cell Proliferation/drug effects; Coculture Techniques; Dose-Response Relationship, Drug; Fas Ligand Protein/metabolism; Humans; Jurkat Cells; Leukocytes, Mononuclear/cytology; Leukocytes, Mononuclear/drug effects; Leukocytes, Mononuclear/metabolism; Lymphocyte Activation/drug effects; Lymphocyte Activation/immunology; Mice; NIH 3T3 Cells; Protein Binding/drug effects; Recombinant Fusion Proteins/metabolism; T-Lymphocytes/cytology; T-Lymphocytes/metabolism; Transfection; fas Receptor/metabolism

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Fusion Proteins / T-Lymphocytes / Apoptosis / CD40 Antigens / Fas Ligand Protein Language: En Journal: Int Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2007 Type: Article Affiliation country: Israel

Search on Google

XML

PubMed Links