Attenuated cytotoxicity but enhanced betafibril of a mutant amyloid beta-peptide with a methionine to cysteine substitution.

Dai, Xue-Ling; Sun, Ya-Xuan; Jiang, Zhao-Feng

Dai, Xue-Ling; Sun, Ya-Xuan; Jiang, Zhao-Feng.

Affiliation

Dai XL; College of Life Science, Capital Normal University, Beijing 100037, China.

FEBS Lett ; 581(7): 1269-74, 2007 Apr 03.

Article in En | MEDLINE | ID: mdl-17349630

Subject(s)

Amyloid beta-Peptides/chemistry; Amyloid beta-Peptides/toxicity; Amyloid/chemistry; Neurons/drug effects; Peptide Fragments/chemistry; Peptide Fragments/toxicity; Amino Acid Sequence; Amino Acid Substitution; Amyloid beta-Peptides/chemical synthesis; Animals; Cells, Cultured; Circular Dichroism; Cysteine/chemistry; Humans; Methionine/chemistry; Molecular Sequence Data; Peptide Fragments/chemical synthesis; Protein Structure, Secondary; Rats

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Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Amyloid beta-Peptides / Amyloid / Neurons Limits: Animals / Humans Language: En Journal: FEBS Lett Year: 2007 Type: Article Affiliation country: China

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