Expression level of Bcl-XL critically affects sensitivity of hepatocellular carcinoma cells to LIGHT-enhanced and interferon-gamma-induced apoptosis.

Li, Jun; Shen, Feng; Wu, Dong; Wei, Li-Xin; Wang, Yi-Zhen; Shi, Le-Hua; Zou, Ying; Wu, Meng-Chao

Li, Jun; Shen, Feng; Wu, Dong; Wei, Li-Xin; Wang, Yi-Zhen; Shi, Le-Hua; Zou, Ying; Wu, Meng-Chao.

Affiliation

Li J; Division of Comprehensive Treatment, Eastern Hepatobiliary Hospital, Second Military Medical University, Shanghai 200438, PR China.

Oncol Rep ; 17(5): 1067-75, 2007 May.

Article in En | MEDLINE | ID: mdl-17390046

Subject(s)

Apoptosis/physiology; Carcinoma, Hepatocellular/pathology; Interferon-gamma/pharmacology; Liver Neoplasms/pathology; Tumor Necrosis Factor Ligand Superfamily Member 14/pharmacology; bcl-X Protein/biosynthesis; Apoptosis/drug effects; Carcinoma, Hepatocellular/drug therapy; Carcinoma, Hepatocellular/metabolism; Cell Line, Tumor; Down-Regulation; Humans; Liver Neoplasms/drug therapy; Liver Neoplasms/metabolism; Lymphotoxin beta Receptor/metabolism; RNA, Small Interfering/genetics; Receptors, Tumor Necrosis Factor, Member 14/metabolism; Recombinant Proteins/pharmacology; STAT3 Transcription Factor/metabolism; Signal Transduction; Transfection; Tumor Necrosis Factor Ligand Superfamily Member 14/biosynthesis; Tumor Necrosis Factor Ligand Superfamily Member 14/genetics; bcl-X Protein/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Interferon-gamma / Apoptosis / Carcinoma, Hepatocellular / Bcl-X Protein / Tumor Necrosis Factor Ligand Superfamily Member 14 / Liver Neoplasms Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Oncol Rep Journal subject: NEOPLASIAS Year: 2007 Type: Article

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