Complex chromosome 8;21 translocation with associated hyperdiploidy in acute myeloid leukemia (FAB-M2).

Corral, María del Pilar; Villa, Olaya; Alfaro, Elizabeth M; Alonso, Cristina N; Baro, Cristina; Felice, Maria S; Rossi, Jorge; Solé, Francesc; Gallego, Marta S

Corral, María del Pilar; Villa, Olaya; Alfaro, Elizabeth M; Alonso, Cristina N; Baro, Cristina; Felice, Maria S; Rossi, Jorge; Solé, Francesc; Gallego, Marta S.

Affiliation

Corral Mdel P; Cytogenetics Laboratory, Department of Genetics, Hospital de Pediatria SAMIC "Prof. Dr. J P Garrahan", Buenos Aires, Argentina.

Pediatr Blood Cancer ; 50(3): 651-4, 2008 Mar.

Article in En | MEDLINE | ID: mdl-17405156

Subject(s)

Aneuploidy; Chromosomes, Human, Pair 21/ultrastructure; Chromosomes, Human, Pair 8/ultrastructure; Core Binding Factor Alpha 2 Subunit/genetics; Leukemia, Myeloid, Acute/genetics; Oncogene Proteins, Fusion/genetics; Translocation, Genetic; Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Child; Chromosomes, Human, Pair 21/genetics; Chromosomes, Human, Pair 8/genetics; Cytarabine/administration & dosage; Cytogenetic Analysis; Etoposide/administration & dosage; Humans; Idarubicin/administration & dosage; Leukemia, Myeloid, Acute/drug therapy; Male; Nucleic Acid Hybridization; Polymerase Chain Reaction; RUNX1 Translocation Partner 1 Protein

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Collection: 01-internacional Database: MEDLINE Main subject: Translocation, Genetic / Chromosomes, Human, Pair 8 / Chromosomes, Human, Pair 21 / Leukemia, Myeloid, Acute / Oncogene Proteins, Fusion / Core Binding Factor Alpha 2 Subunit / Aneuploidy Type of study: Guideline / Prognostic_studies / Risk_factors_studies Limits: Child / Humans / Male Language: En Journal: Pediatr Blood Cancer Journal subject: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Year: 2008 Type: Article Affiliation country: Argentina

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