Protective effects of hepatocellular canalicular conjugate export pump (Mrp2) on sodium arsenite-induced hepatic dysfunction in rats.

Li, Guo-Xing; Pei, Qiu-Ling; Gao, Yi; Liu, Ke-Ming; Nie, Ji-Sheng; Han, Guang; Qiu, Yu-Lan; Zhang, Wen-Ping

Li, Guo-Xing; Pei, Qiu-Ling; Gao, Yi; Liu, Ke-Ming; Nie, Ji-Sheng; Han, Guang; Qiu, Yu-Lan; Zhang, Wen-Ping.

Affiliation

Li GX; Tianjin Centers for Disease Control and Prevention, Hedong District, Tianjin, PR China.

Exp Toxicol Pathol ; 58(6): 447-53, 2007 Aug.

Article in En | MEDLINE | ID: mdl-17467962

Subject(s)

ATP-Binding Cassette Transporters/metabolism; Arsenic Poisoning/blood; Arsenites/toxicity; Chemical and Drug Induced Liver Injury/blood; Enzyme Inhibitors/toxicity; Liver/drug effects; Sodium Compounds/toxicity; Alanine Transaminase/blood; Animals; Arsenic/blood; Arsenic Poisoning/pathology; Arsenites/metabolism; Aspartate Aminotransferases/blood; Bile/chemistry; Bile/metabolism; Bile Canaliculi/drug effects; Bile Canaliculi/ultrastructure; Bilirubin/blood; Blotting, Western; Chemical and Drug Induced Liver Injury/etiology; Chemical and Drug Induced Liver Injury/pathology; Enzyme Inhibitors/metabolism; Female; Glutathione Peroxidase/blood; Liver/metabolism; Male; Malondialdehyde/blood; Rats; Rats, Wistar; Sodium Compounds/metabolism; Spectrophotometry, Atomic

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Sodium Compounds / Arsenites / ATP-Binding Cassette Transporters / Arsenic Poisoning / Enzyme Inhibitors / Chemical and Drug Induced Liver Injury / Liver Type of study: Etiology_studies Limits: Animals Language: En Journal: Exp Toxicol Pathol Journal subject: PATOLOGIA / TOXICOLOGIA Year: 2007 Type: Article

Search on Google

XML

PubMed Links