Alteration of antigen-independent immunologic synapse formation between dendritic cells from HLA-B27-transgenic rats and CD4+ T cells: selective impairment of costimulatory molecule engagement by mature HLA-B27.

Hacquard-Bouder, Cécile; Chimenti, Maria-Sole; Giquel, Benoît; Donnadieu, Emmanuel; Fert, Ingrid; Schmitt, Alain; André, Claudine; Breban, Maxime

Hacquard-Bouder, Cécile; Chimenti, Maria-Sole; Giquel, Benoît; Donnadieu, Emmanuel; Fert, Ingrid; Schmitt, Alain; André, Claudine; Breban, Maxime.

Affiliation

Hacquard-Bouder C; Institut Cochin, Université René Descartes, CNRS (VMR 8104), Paris, INSERM U 567, Paris, France.

Arthritis Rheum ; 56(5): 1478-89, 2007 May.

Article in En | MEDLINE | ID: mdl-17469106

Subject(s)

CD4-Positive T-Lymphocytes/immunology; Dendritic Cells/immunology; HLA-B27 Antigen/genetics; HLA-B27 Antigen/physiology; Spondylarthropathies/immunology; Synapses/immunology; Tumor Necrosis Factor Receptor Superfamily, Member 7/physiology; Animals; Animals, Genetically Modified; CD4-Positive T-Lymphocytes/cytology; Cell Communication/physiology; Cell Movement/immunology; Dendritic Cells/cytology; Disease Models, Animal; Female; Male; Rats; Rats, Inbred F344; Spondylarthropathies/genetics; Spondylarthropathies/pathology

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Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Dendritic Cells / CD4-Positive T-Lymphocytes / HLA-B27 Antigen / Tumor Necrosis Factor Receptor Superfamily, Member 7 / Spondylarthropathies Type of study: Prognostic_studies Limits: Animals Language: En Journal: Arthritis Rheum Year: 2007 Type: Article Affiliation country: France

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