A Cul3-based E3 ligase removes Aurora B from mitotic chromosomes, regulating mitotic progression and completion of cytokinesis in human cells.

Sumara, Izabela; Quadroni, Manfredo; Frei, Claudia; Olma, Michael H; Sumara, Grzegorz; Ricci, Romeo; Peter, Matthias

Sumara, Izabela; Quadroni, Manfredo; Frei, Claudia; Olma, Michael H; Sumara, Grzegorz; Ricci, Romeo; Peter, Matthias.

Affiliation

Sumara I; Institute of Biochemistry, ETH Zurich, 8093 Zurich, Switzerland. izabela.sumara@bc.biol.ethz.ch

Dev Cell ; 12(6): 887-900, 2007 Jun.

Article in En | MEDLINE | ID: mdl-17543862

Subject(s)

Cell Cycle Proteins/metabolism; Chromosomes, Human; Cullin Proteins/metabolism; Cytokinesis; Mitosis; Protein Serine-Threonine Kinases/metabolism; Ubiquitin-Protein Ligase Complexes/metabolism; Aurora Kinase B; Aurora Kinases; Cell Cycle Proteins/genetics; Cullin Proteins/genetics; HeLa Cells; Humans; Protein Serine-Threonine Kinases/genetics; Spindle Apparatus; Ubiquitin/metabolism; Ubiquitin-Protein Ligase Complexes/genetics; Ubiquitin-Protein Ligases/genetics; Ubiquitin-Protein Ligases/metabolism

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Chromosomes, Human / Protein Serine-Threonine Kinases / Cell Cycle Proteins / Ubiquitin-Protein Ligase Complexes / Cullin Proteins / Cytokinesis / Mitosis Type of study: Prognostic_studies Limits: Humans Language: En Journal: Dev Cell Journal subject: EMBRIOLOGIA Year: 2007 Type: Article Affiliation country: Switzerland

Search on Google

XML

PubMed Links