Epidermal growth factor receptor (EGFR) mutation does not correlate with platinum resistance in ovarian carcinoma. Results of a prospective pilot study.

Mustea, Alexander; Sehouli, Jalid; Fabjani, Gerhild; Koensgen, Dominique; Möbus, V; Braicu, Elena Ioana; Pirvulescu, Cristina; Thomas, Anke; Tong, Dan; Zeillinger, Robert

Mustea, Alexander; Sehouli, Jalid; Fabjani, Gerhild; Koensgen, Dominique; Möbus, V; Braicu, Elena Ioana; Pirvulescu, Cristina; Thomas, Anke; Tong, Dan; Zeillinger, Robert.

Affiliation

Mustea A; Department of Gynaecology and Obstetrics, Charité, Medical University of Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany. alexander.mustea@charite.de

Anticancer Res ; 27(3B): 1527-30, 2007.

Article in En | MEDLINE | ID: mdl-17595771

Subject(s)

Antineoplastic Agents/therapeutic use; Carcinoma/drug therapy; Drug Resistance, Neoplasm/genetics; ErbB Receptors/genetics; Ovarian Neoplasms/drug therapy; Platinum Compounds/therapeutic use; Adult; Aged; Carcinoma/mortality; Carcinoma/surgery; DNA Mutational Analysis; Female; Humans; Middle Aged; Mutation, Missense; Ovarian Neoplasms/mortality; Ovarian Neoplasms/surgery; Pilot Projects; Prospective Studies; Sequence Deletion; Survival

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Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Carcinoma / Platinum Compounds / Drug Resistance, Neoplasm / ErbB Receptors / Antineoplastic Agents Type of study: Observational_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Anticancer Res Year: 2007 Type: Article Affiliation country: Germany

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