Chloroform extract of deer antler inhibits osteoclast differentiation and bone resorption.

Li, Yin-Ji; Kim, Tae-Hee; Kwak, Han Bok; Lee, Zang Hee; Lee, Soo-Young; Jhon, Gil-Ja

Li, Yin-Ji; Kim, Tae-Hee; Kwak, Han Bok; Lee, Zang Hee; Lee, Soo-Young; Jhon, Gil-Ja.

Affiliation

Li YJ; Division of Molecular Life Sciences and Center for Cell Signaling Research, Ewha Womans University, Seoul, Republic of Korea.

J Ethnopharmacol ; 113(2): 191-8, 2007 Sep 05.

Article in En | MEDLINE | ID: mdl-17646068

Subject(s)

Antlers/chemistry; Bone Resorption/prevention & control; Cell Differentiation/drug effects; Deer; Osteoclasts/drug effects; Tissue Extracts/pharmacology; Actins/metabolism; Adaptor Proteins, Signal Transducing/metabolism; Animals; Apoptosis/drug effects; Bone Marrow Cells/cytology; Bone Marrow Cells/drug effects; Bone Marrow Cells/metabolism; Bone Resorption/metabolism; Bone Resorption/pathology; Cell Survival/drug effects; Cells, Cultured; Chloroform/chemistry; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases/metabolism; Macrophages/cytology; Macrophages/drug effects; Macrophages/metabolism; Mice; Mice, Inbred C57BL; NF-kappa B/metabolism; Osteoblasts/cytology; Osteoblasts/drug effects; Osteoblasts/metabolism; Osteoclasts/cytology; Osteoclasts/metabolism; Phosphorylation/drug effects; Proto-Oncogene Proteins c-akt/metabolism; RANK Ligand/pharmacology; Tissue Extracts/chemistry; Tissue Extracts/isolation & purification

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Collection: 01-internacional Database: MEDLINE Main subject: Antlers / Osteoclasts / Tissue Extracts / Bone Resorption / Deer / Cell Differentiation Limits: Animals Language: En Journal: J Ethnopharmacol Year: 2007 Type: Article

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