Biochemical characterization of USP7 reveals post-translational modification sites and structural requirements for substrate processing and subcellular localization.

Fernández-Montalván, Amaury; Bouwmeester, Tewis; Joberty, Gerard; Mader, Robert; Mahnke, Marion; Pierrat, Benoit; Schlaeppi, Jean-Marc; Worpenberg, Susanne; Gerhartz, Bernd

Fernández-Montalván, Amaury; Bouwmeester, Tewis; Joberty, Gerard; Mader, Robert; Mahnke, Marion; Pierrat, Benoit; Schlaeppi, Jean-Marc; Worpenberg, Susanne; Gerhartz, Bernd.

Affiliation

Fernández-Montalván A; Expertise Platform Proteases, Novartis Institutes for Biomedical Research, Basel, Switzerland. amaury.fernandez@merckserono.net

FEBS J ; 274(16): 4256-70, 2007 Aug.

Article in En | MEDLINE | ID: mdl-17651432

Subject(s)

Cell Nucleus/metabolism; Cytosol/metabolism; Protein Processing, Post-Translational; Ubiquitin Thiolesterase/metabolism; Amino Acid Sequence; Binding Sites; Catalytic Domain/genetics; Cell Line; Cell Line, Tumor; Chromatography, Gel; Dimerization; Green Fluorescent Proteins/genetics; Green Fluorescent Proteins/metabolism; HeLa Cells; Humans; Immunoblotting; Kinetics; Mass Spectrometry; Microscopy, Confocal; Molecular Sequence Data; Molecular Weight; Mutation; Protein Transport; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/metabolism; Substrate Specificity; Transfection; Ubiquitin Thiolesterase/chemistry; Ubiquitin Thiolesterase/genetics; Ubiquitin-Specific Peptidase 7

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Collection: 01-internacional Database: MEDLINE Main subject: Cell Nucleus / Protein Processing, Post-Translational / Cytosol / Ubiquitin Thiolesterase Limits: Humans Language: En Journal: FEBS J Journal subject: BIOQUIMICA Year: 2007 Type: Article Affiliation country: Switzerland

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