B cell activator PAX5 promotes lymphomagenesis through stimulation of B cell receptor signaling.

Cozma, Diana; Yu, Duonan; Hodawadekar, Suchita; Azvolinsky, Anna; Grande, Shannon; Tobias, John W; Metzgar, Michele H; Paterson, Jennifer; Erikson, Jan; Marafioti, Teresa; Monroe, John G; Atchison, Michael L; Thomas-Tikhonenko, Andrei

Cozma, Diana; Yu, Duonan; Hodawadekar, Suchita; Azvolinsky, Anna; Grande, Shannon; Tobias, John W; Metzgar, Michele H; Paterson, Jennifer; Erikson, Jan; Marafioti, Teresa; Monroe, John G; Atchison, Michael L; Thomas-Tikhonenko, Andrei.

Affiliation

Cozma D; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6051, USA.

J Clin Invest ; 117(9): 2602-10, 2007 Sep.

Article in En | MEDLINE | ID: mdl-17717600

Subject(s)

B-Lymphocytes/immunology; B-Lymphocytes/metabolism; Lymphoma/metabolism; Lymphoma/pathology; PAX5 Transcription Factor/metabolism; Receptors, Antigen, B-Cell/metabolism; Animals; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic/metabolism; Cell Transformation, Neoplastic/pathology; Gene Expression Regulation, Neoplastic; Humans; Lymphocyte Activation/immunology; Lymphoma/genetics; Lymphoma/immunology; Mice; Neoplasm Transplantation; PAX5 Transcription Factor/genetics; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Receptors, Antigen, B-Cell / PAX5 Transcription Factor / Lymphoma Limits: Animals / Humans Language: En Journal: J Clin Invest Year: 2007 Type: Article Affiliation country: United States

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