Decitabine up-regulates S100A2 expression and synergizes with IFN-gamma to kill uveal melanoma cells.

Gollob, Jared A; Sciambi, Catherine J

Gollob, Jared A; Sciambi, Catherine J.

Affiliation

Gollob JA; Division of Medical Oncology, Department of Medicine, Duke University, Durham, NC 27710, USA. jared.gollob@duke.edu

Clin Cancer Res ; 13(17): 5219-25, 2007 Sep 01.

Article in En | MEDLINE | ID: mdl-17785578

Subject(s)

Antimetabolites, Antineoplastic/pharmacology; Azacitidine/analogs & derivatives; Chemotactic Factors/genetics; Gene Expression Regulation, Neoplastic/drug effects; Interferon-gamma/pharmacology; Melanoma/drug therapy; S100 Proteins/genetics; Uveal Neoplasms/drug therapy; Apoptosis/drug effects; Azacitidine/pharmacology; Decitabine; Drug Synergism; Humans; Interferon-alpha/pharmacology; Melanoma/metabolism; Melanoma/pathology; Tumor Cells, Cultured; Uveal Neoplasms/metabolism; Uveal Neoplasms/pathology

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Collection: 01-internacional Database: MEDLINE Main subject: Azacitidine / Uveal Neoplasms / S100 Proteins / Gene Expression Regulation, Neoplastic / Chemotactic Factors / Interferon-gamma / Melanoma / Antimetabolites, Antineoplastic Limits: Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2007 Type: Article Affiliation country: United States

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