Neurodegeneration and chronic renal failure in methylmalonic aciduria--a pathophysiological approach.

Morath, M A; Okun, J G; Müller, I B; Sauer, S W; Hörster, F; Hoffmann, G F; Kölker, S

Morath, M A; Okun, J G; Müller, I B; Sauer, S W; Hörster, F; Hoffmann, G F; Kölker, S.

Affiliation

Morath MA; Department of General Pediatrics, Division of Inherited Metabolic Diseases, University Children's Hospital Heidelberg, Im Neuenheimer Feld 150, 69120, Heidelberg, Germany. marina.morath@med.uni-heidelberg.de

J Inherit Metab Dis ; 31(1): 35-43, 2008 Feb.

Article in En | MEDLINE | ID: mdl-17846917

Subject(s)

Kidney Failure, Chronic/etiology; Methylmalonic Acid/urine; Neurodegenerative Diseases/etiology; Vitamin B 12 Deficiency/complications; Animals; Brain/metabolism; Brain/physiopathology; Dicarboxylic Acids/metabolism; Energy Metabolism/physiology; Humans; Kidney/metabolism; Kidney/physiopathology; Kidney Failure, Chronic/metabolism; Kidney Failure, Chronic/therapy; Mitochondria/metabolism; Models, Biological; Neurodegenerative Diseases/metabolism; Neurodegenerative Diseases/therapy; Vitamin B 12 Deficiency/metabolism; Vitamin B 12 Deficiency/urine

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Collection: 01-internacional Database: MEDLINE Main subject: Vitamin B 12 Deficiency / Neurodegenerative Diseases / Kidney Failure, Chronic / Methylmalonic Acid Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: J Inherit Metab Dis Year: 2008 Type: Article Affiliation country: Germany

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