Physiological fever temperature induces a protective stress response in T lymphocytes mediated by heat shock factor-1 (HSF1).

Murapa, Patience; Gandhapudi, Siva; Skaggs, Hollie S; Sarge, Kevin D; Woodward, Jerold G

Murapa, Patience; Gandhapudi, Siva; Skaggs, Hollie S; Sarge, Kevin D; Woodward, Jerold G.

Affiliation

Murapa P; Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky Medical Center, Lexington 40536, USA.

J Immunol ; 179(12): 8305-12, 2007 Dec 15.

Article in En | MEDLINE | ID: mdl-18056375

Subject(s)

Body Temperature/immunology; DNA-Binding Proteins/physiology; Fever/immunology; T-Lymphocytes/immunology; Transcription Factors/physiology; Animals; Cell Proliferation; DNA-Binding Proteins/genetics; G1 Phase/genetics; G1 Phase/immunology; HSP70 Heat-Shock Proteins/metabolism; Heat Shock Transcription Factors; Lymphocyte Activation; Mice; Mice, Knockout; Reactive Oxygen Species/metabolism; S Phase/genetics; S Phase/immunology; Transcription Factors/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Body Temperature / T-Lymphocytes / DNA-Binding Proteins / Fever Limits: Animals Language: En Journal: J Immunol Year: 2007 Type: Article Affiliation country: United States

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