Neuralized contains a phosphoinositide-binding motif required downstream of ubiquitination for delta endocytosis and notch signaling.

Skwarek, Lara C; Garroni, Michael K; Commisso, Cosimo; Boulianne, Gabrielle L

Skwarek, Lara C; Garroni, Michael K; Commisso, Cosimo; Boulianne, Gabrielle L.

Affiliation

Skwarek LC; The Hospital for Sick Children, Program in Developmental and Stem Cell Biology, Toronto, Ontario M5G 1X8, Canada.

Dev Cell ; 13(6): 783-95, 2007 Dec.

Article in En | MEDLINE | ID: mdl-18061562

Subject(s)

Drosophila Proteins/metabolism; Drosophila melanogaster/metabolism; Endocytosis/physiology; Membrane Proteins/metabolism; Phosphatidylinositols/metabolism; Signal Transduction/physiology; Ubiquitin-Protein Ligases/metabolism; Amino Acid Motifs; Animals; Animals, Genetically Modified; Blotting, Western; Cell Membrane/metabolism; Drosophila Proteins/genetics; Drosophila melanogaster/embryology; Drosophila melanogaster/growth & development; Embryo, Nonmammalian/cytology; Embryo, Nonmammalian/metabolism; Female; Fluorescent Antibody Technique; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Male; Membrane Lipids/metabolism; Membrane Proteins/genetics; Mutagenesis; Receptors, Notch/genetics; Receptors, Notch/metabolism; Ubiquitin/metabolism; Ubiquitin-Protein Ligases/genetics; Ubiquitination

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Collection: 01-internacional Database: MEDLINE Main subject: Phosphatidylinositols / Signal Transduction / Drosophila Proteins / Ubiquitin-Protein Ligases / Drosophila melanogaster / Endocytosis / Membrane Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: Dev Cell Journal subject: EMBRIOLOGIA Year: 2007 Type: Article Affiliation country: Canada

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