A recombinant human receptor antagonist to interleukin 1 improves survival after lethal endotoxemia in mice.

Alexander, H R; Doherty, G M; Buresh, C M; Venzon, D J; Norton, J A

Alexander, H R; Doherty, G M; Buresh, C M; Venzon, D J; Norton, J A.

Affiliation

Alexander HR; Surgical Metabolism Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.

J Exp Med ; 173(4): 1029-32, 1991 Apr 01.

Article in En | MEDLINE | ID: mdl-1826127

Subject(s)

Endotoxins/toxicity; Proteins/pharmacology; Receptors, Immunologic/antagonists & inhibitors; Sialoglycoproteins; Animals; Endotoxins/blood; Escherichia coli; Female; Interleukin 1 Receptor Antagonist Protein; Lipopolysaccharides/antagonists & inhibitors; Mice; Mice, Inbred C57BL; Receptors, Interleukin-1; Time Factors; Tumor Necrosis Factor-alpha/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sialoglycoproteins / Receptors, Immunologic / Proteins / Endotoxins Limits: Animals Language: En Journal: J Exp Med Year: 1991 Type: Article

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